The central government has imposed an immediate ban on the manufacture, sale and distribution of all oral formulations of the painkiller nimesulide containing more than 100 mg in immediate-release form, citing risks to human health and the availability of safer alternatives. The decision, taken under the Drugs and Cosmetics Act after expert consultation, was notified by the health ministry. Separately, the ministry proposed changes to the Drugs Rules, inviting public feedback within 30 days.